Month: February 2025

In addition to transmitting translation knowledge, translators in this article are seen to interpret what their experiences mean in their professional and personal lives, especially within the context of social, cultural, and political shifts, ultimately promoting a more translator-focused perspective on translation knowledge.

This study focused on determining the significant themes to incorporate when modifying mental health treatments for visually impaired adults.
Thirty-seven experts, encompassing professionals, individuals with visual impairments, and relatives of clients with visual impairments, were part of a Delphi study.
Seven significant factors emerged from a Delphi consultation regarding mental health treatment for clients with visual impairments: the client's visual impairment, environmental context, stress triggers, emotional responses, the professional's conduct, the treatment location, and access to materials. Treatment adaptations for clients with visual impairments are determined by the severity of those impairments. While undergoing treatment, the expert plays a key role in providing clarification on any visual elements that a client with a visual impairment might not perceive.
Visual impairment necessitates individualized therapeutic adjustments for clients undergoing psychological treatment.
Clients in psychological treatment benefit from visual adaptations specifically designed to address their individual visual impairment needs.

The utilization of obex might prove beneficial in curbing body weight and fat accumulation. Overweight and obese subjects were the focus of this research, which aimed to evaluate the efficacy and safety of Obex's application.
In a double-blind, randomized, controlled design, a phase III clinical trial was carried out on 160 overweight and obese subjects (BMI range 25.0-40 kg/m²).
Eighty participants aged 20-60 years, receiving Obex, and an equivalent number receiving a placebo, were all concurrently undergoing non-pharmacological treatment, consisting of physical activity and dietary counselling. Prior to the two principal meals each day, participants received either one sachet of Obex or a placebo for a duration of six months. Besides anthropometric measurements and blood pressure, fasting plasma and 2-hour glucose levels from the oral glucose tolerance test, a lipid profile, insulin levels, liver enzymes, creatinine, and uric acid (UA) were all measured. Insulin resistance (HOMA-IR), beta-cell function (HOMA-), and insulin sensitivity (IS) were also calculated using three indirect indices.
Following three months of the Obex regimen, 483% (28 of 58) participants achieved a complete reduction of weight and waist circumference by 5% or greater from their initial levels; this result significantly outperformed the placebo group's 260% (13 of 50) success rate (p=0.0022). Observing six months from baseline, no changes were found in anthropometric and biochemical measures across groups, apart from high-density lipoprotein cholesterol (HDL-c), which demonstrated higher levels in the Obex cohort compared to the placebo cohort (p=0.030). Following six months of treatment, both cohorts exhibited a decrease in cholesterol and triglyceride levels, as indicated by a p-value less than 0.012, when compared to baseline measurements. Among the treatment groups, only those administered Obex showed a decrease in insulin levels, a drop in HOMA-IR, an improvement in insulin sensitivity (p<0.005), and a reduction in creatinine and uric acid (p<0.0005).
Integrating Obex into a lifestyle modification program yielded elevated HDL-c, a rapid reduction in weight and waist circumference, and improved insulin balance—findings not replicated in the placebo group—indicating its potential safety when used alongside standard obesity treatments.
The clinical trial protocol, with registration code RPCEC00000267, was recorded in the Cuban public registry on April 17th, 2018, and subsequently entered into the international ClinicalTrials.gov registry. The 30th of May, 2018, marked a significant date under code NCT03541005.
Registration of the clinical trial protocol in the Cuban public registry occurred on 17/04/2018, using code RPCEC00000267. It was simultaneously registered with the international ClinicalTrials.gov registry. The 30th of May, 2018, was the date for the implementation of the code NCT03541005.

The investigation of organic room-temperature phosphorescence (RTP) for the creation of long-lived luminescent materials has been substantial. An important aspect of this research is improving the efficiency of red and near-infrared (NIR) RTP molecules. However, the lack of rigorous studies on the linkage between fundamental molecular architectures and luminescence properties means that the variety and amount of red and NIR RTP molecules are still far from satisfying the demands of practical applications. Employing density functional theory (DFT) and time-dependent density functional theory (TD-DFT), the photophysical characteristics of seven red and near-infrared (NIR) RTP molecules were computationally examined in tetrahydrofuran (THF) and solid form. A polarizable continuum model (PCM) for THF and a quantum mechanics/molecular mechanics (QM/MM) method for the solid phase were employed to investigate excited-state dynamic processes by calculating the intersystem crossing and reverse intersystem crossing rates, which accounts for environmental effects. Geometric and electronic data were gathered, Huang-Rhys factors and reorganization energies were scrutinized, and natural atomic orbitals were employed to quantify excited-state orbital information. A concurrent analysis of the electrostatic potential distribution on the molecular surfaces was performed. By means of the Hirshfeld partition, the independent gradient model for molecular planarity (IGMH) was applied to illustrate intermolecular interactions. this website The experiment's conclusion highlighted the potential of the unique molecular formation to result in red and near-infrared (NIR) RTP emission. Substituting halogen and sulfur produced a red-shift in the emission wavelength, while the linkage of the two cyclic imide groups simultaneously extended the wavelength. Beyond that, the emission characteristics of molecules in the THF environment mirrored the trend observed in the solid phase. structured medication review Consequently, two hypothetical RTP molecules with emission wavelengths of 645 nm and 816 nm are introduced, followed by a comprehensive exploration of their photophysical behavior. An investigation into the design of efficient and long-emitting RTP molecules, incorporating an unconventional luminescence group, unveils a sound strategy.

Patients requiring surgical treatment from remote communities often relocate to urban centers for care. Examining the care pathway, this study analyzes the timeline for pediatric surgical patients from two remote Quebec Indigenous communities, seen at the Montreal Children's Hospital. To ascertain the elements that influence length of stay, the study analyzes post-operative complications and the associated risk factors.
The records of children from Nunavik and Terres-Cries-de-la-Baie-James, undergoing general or thoracic surgery between 2011 and 2020, formed the basis of this single-center, retrospective study. Descriptive data was compiled concerning patient traits, potential complications, and postoperative difficulties. The patient's chart was reviewed to determine the timeline from the initial consultation to the subsequent post-operative follow-up, specifying the dates and the chosen method of follow-up.
The analysis of 271 eligible cases revealed 213 urgent procedures (a total of 798%) and 54 elective procedures (a total of 202%). During the follow-up assessments, postoperative complications were noted in four of the patients (15% total). Complications were confined to patients undergoing urgent surgical procedures. Surgical site infections, 75% of the three complications, were managed using conservative methods. Amongst those electing for elective surgery, a proportion of 20% experienced a wait exceeding five days prior to the procedure. This was the main contributor to the total time spent during the Montreal visit.
Only urgent surgical procedures resulted in postoperative complications identified at the one-week follow-up. This rarity strongly implies that telemedicine can effectively substitute many in-person post-surgical follow-up appointments. There is scope for improvement in wait times for those from remote communities, by prioritizing those patients who have been displaced whenever possible.
Only a small number of postoperative complications were detected during the one-week follow-up, and these were limited to patients requiring urgent surgical intervention. This suggests that remote consultations can safely replace numerous in-person post-operative visits. In addition, the current wait times for those in remote communities can be addressed by providing preferential treatment to those who have been displaced, if possible.

Japanese publications are experiencing a downturn, a trend anticipated to persist due to the shrinking population. Antibiotic de-escalation A concerning trend emerged during the COVID-19 pandemic: Japanese medical trainees published significantly fewer research papers compared to trainees from other countries. The entire Japanese medical community has a responsibility to address this issue. Trainees can enrich the medical community by effectively utilizing publishing platforms and social media to disseminate original perspectives and accurate information to the public. Furthermore, the in-depth and critical examination of worldwide publications will yield significant benefits for trainees, ultimately promoting the broader application of evidence-based medicine. Subsequently, medical educators and students should be driven and motivated to author by affording them ample instructional and publishing opportunities.

The post-operative development of surgical mesh infection (SMI) following abdominal wall hernia repair (AWHR) is a challenging and intensely debated clinical matter, currently lacking a standard approach. This analysis of the literature centered on negative pressure wound therapy (NPWT) in the conservative approach to SMI, with a focus on the results of salvaging infected meshes.
A comprehensive analysis of NPWT in treating SMI patients after experiencing AWHR, based on a systematic review of EMBASE and PUBMED, was conducted. The collected articles were reviewed to determine the connection between clinical, demographic, analytical, and surgical characteristics in SMI patients after AWHR. The substantial diversity within these studies precluded a meaningful meta-analysis of outcomes.
Through a search strategy, PubMed provided 33 studies and EMBASE delivered 16 studies in response. NPWT was performed on 230 patients across 9 studies, with mesh salvage achieved in 196 (85.2%) of the cases. Of the total 230 cases, 46% were categorized as polypropylene (PPL), 99% as polyester (PE), 168% as polytetrafluoroethylene (PTFE), 4% as biologic, and a further 102% utilized a composite mesh of polypropylene (PPL) and polytetrafluoroethylene (PTFE). The distribution of mesh infection sites included the onlay location in 43% of patients, retromuscular site in 22%, preperitoneal region in 19%, intraperitoneal position in 10%, and placement between the oblique muscles in 5%. For optimal salvageability outcomes, NPWT treatment strategies leveraging macroporous PPL mesh in the extraperitoneal space (192% onlay, 233% preperitoneal, 488% retromuscular) proved most effective.
After AWHR, NPWT is a suitable treatment strategy for SMI. This approach often permits the retention of function in contaminated prostheses. To ensure the generalizability of our analysis results, a larger sample size is necessary in future studies.
SMI subsequent to AWHR is effectively managed by NPWT. Salvaging infected prostheses is frequently achievable with this intervention. To strengthen the reliability of our findings, additional research with a larger sample size is imperative.

The optimal means of determining the frailty grade in cancer patients undergoing esophagectomy for esophageal cancer is still under investigation. brain histopathology In esophagectomized esophageal cancer patients, this research aimed to clarify the correlation between cachexia index (CXI) and osteopenia with survival, leading to the creation of a frailty-based prognostic risk assessment.
A comprehensive study of 239 patients who underwent esophagectomy was undertaken. A calculation involving serum albumin and the neutrophil-to-lymphocyte ratio yielded the skeletal muscle index, designated as CXI. Simultaneously, osteopenia was diagnosed based on bone mineral density (BMD) measurements which were below the cutoff point defined by the receiver operating characteristic curve. Digital PCR Systems Preoperative computed tomography images were employed to quantify the mean Hounsfield unit value within a circle encompassing the lower midvertebral core of the 11th thoracic vertebra. This value was representative of bone mineral density (BMD).
Through a multivariate analysis, low CXI (hazard ratio [HR] 195; 95% confidence interval [CI] 125-304) and osteopenia (HR 186; 95% CI 119-293) were independently identified as significant prognostic factors for overall survival. In addition, low CXI (hazard ratio: 158; 95% confidence interval: 106-234) and osteopenia (hazard ratio: 157; 95% confidence interval: 105-236) emerged as statistically significant prognostic factors for relapse-free survival. Four prognostic groups were established based on the combination of frailty grade, CXI, and osteopenia.
Esophagectomy for esophageal cancer, characterized by low CXI and osteopenia, correlates with a poor prognosis for survival. Concomitantly, a new frailty grade, alongside CXI and osteopenia, formed four patient groups based on their predicted prognosis.
Poor survival outcomes are associated with low CXI and osteopenia in patients undergoing esophagectomy for esophageal cancer. Concurrently, a novel frailty scale, incorporating CXI and osteopenia, differentiated patients into four prognostic groups.

Evaluating the security and potency of a complete circumferential trabeculotomy (TO) procedure for managing short-term steroid-induced glaucoma (SIG) is the aim of this study.
Retrospective surgical outcomes in 35 patients (comprising 46 eyes) undergoing microcatheter-assisted TO were examined. All eyes presented with elevated intraocular pressure, a consequence of steroid use, which persisted for approximately no more than three years. A study's follow-up period encompassed times from 263 to 479 months, calculating to a mean of 239 months and a median of 256 months.
Before the commencement of the surgery, the intraocular pressure (IOP) stood at a remarkably high 30883 mm Hg, necessitating the utilization of 3810 medications designed to lower pressure. A mean intraocular pressure (IOP) of 11226 mm Hg (n=28) was found in the group after 1-2 years. The average number of IOP-lowering medications was 0913. Following their recent check-up, 45 eyes exhibited an intraocular pressure (IOP) of less than 21mm Hg, while 39 eyes experienced an IOP below 18mm Hg, possibly with or without supplemental medication. After a two-year observation, the anticipated probability of an intraocular pressure (IOP) reading below 18mm Hg (with or without medication) reached 856%, corresponding to a 567% estimated probability of foregoing any medical treatment. A steroid response was not consistently observed in the entire population of eyes that received steroids after surgical procedures. Hyphema, transient hypotony, or hypertony, formed part of the minor complications. One eye's visual impairment was targeted with a glaucoma drainage implant.
TO, with its relatively short duration, achieves outstanding results within the SIG context. The outflow system's pathophysiology is mirrored by this observation. Eyes requiring target pressures within the mid-teens, especially in cases demanding ongoing steroid treatment, appear especially responsive to this procedure.
In the context of SIG, TO's relatively short duration makes it particularly effective. This aligns with the disease process of the outflow system. This procedure demonstrates a particular suitability for eyes in which target pressures within the mid-teens are considered appropriate, especially in cases requiring chronic steroid treatment.

With respect to epidemic arboviral encephalitis, the West Nile virus (WNV) is the predominant cause observed in the United States. In the absence of proven antiviral therapies or licensed human vaccines for WNV, insights into its neuropathogenic mechanisms are critical for the rational design of effective treatments. In the context of WNV infection in mice, the absence of microglia promotes amplified viral replication, more extensive central nervous system (CNS) tissue damage, and greater mortality, emphasizing the crucial protective function of microglia against WNV neuroinvasive disease. We sought to identify whether increasing microglial activation holds therapeutic promise, and to that end, we administered granulocyte-macrophage colony-stimulating factor (GM-CSF) to WNV-infected mice. Chemotherapy or bone marrow transplantation, often accompanied by leukopenia, necessitate the utilization of rHuGM-CSF, also known as sargramostim (Leukine), an FDA-approved drug intended to increase white blood cell levels. selleck products Repeated daily subcutaneous injections of GM-CSF in both uninfected and WNV-infected mice resulted in microglia proliferation and activation, as demonstrated by an increase in Iba1 (ionized calcium binding adaptor molecule 1) and several microglia-associated inflammatory cytokines including CCL2 (C-C motif chemokine ligand 2), interleukin-6 (IL-6), and interleukin-10 (IL-10). In complement, a larger contingent of microglia assumed an activated morphology, underscored by their enlarged size and more pronounced protrusions. GM-CSF's influence on microglial activation in WNV-infected mice led to demonstrably lower viral titers, a decrease in caspase-3-mediated apoptosis in the brain, and a significant rise in the survival of infected mice. Following treatment with GM-CSF, ex vivo brain slice cultures (BSCs) infected with WNV displayed lower viral titers and reduced caspase 3 apoptosis, highlighting the central nervous system specificity of GM-CSF's effects, without involvement of peripheral immune functions. Based on our research, the stimulation of microglial activation presents itself as a possible therapeutic avenue for addressing WNV neuroinvasive disease. Although occurring rarely, WNV encephalitis presents a significant and devastating health challenge, with limited treatment options and the prevalence of long-term neurological complications. Currently, the medical community lacks human vaccines and targeted antivirals for WNV, thus mandating further research into new potential therapeutic agents. This study introduces a novel therapeutic approach to WNV infections, leveraging GM-CSF, and establishes a foundation for further investigations into GM-CSF's potential as a treatment for WNV encephalitis and possibly other viral infections.

The causative agent of the aggressive neurodegenerative ailment HAM/TSP, alongside a variety of neurological changes, is the human T-cell leukemia virus type 1 (HTLV-1). The central nervous system (CNS) resident cell infection capacity of HTLV-1, coupled with the neuroimmune response, remains poorly understood. We investigated HTLV-1 neurotropism by applying human induced pluripotent stem cells (hiPSCs) along with naturally STLV-1-infected non-human primates (NHPs) as representative models. Subsequently, hiPSC-derived neuronal cells cultivated within a neural co-culture environment constituted the predominant population of HTLV-1-infected cells. Furthermore, we document STLV-1 infection in spinal cord neurons, as well as in the cortical and cerebellar regions of the postmortem brain tissue from non-human primates. Furthermore, reactive microglial cells were observed within the affected regions, indicative of an antiviral immune response.

In the results, the mechanical properties of triphase lattices display a balanced performance. Importantly, this finding suggests that a relatively weak phase could enhance stiffness and plateau stress, a distinct contrast to the prevalent mixed rule. This work intends to furnish new references, inspired by material microstructure, for the purpose of designing heterogeneous lattices with remarkable mechanical properties.

In hospitalized patient populations, penicillin allergy labels are a common occurrence, resulting in a widespread misconception regarding their compatibility with cephalosporins. A subsequent examination of past records showed a statistically significant relationship between self-reported penicillin allergies and diminished likelihood of first-line treatment for acute hematogenous osteomyelitis.

This report details a newborn, nine days post-partum, affected by a vesicular rash appearing on the scalp and chest. Mpox virus DNA was detected in vesicular fluid, as confirmed by polymerase chain reaction testing. The incidence of comparable reports in newborns is low. Consequently, Mpox infection should be part of the differential diagnosis for a neonatal vesicular rash, particularly when the family has a history of similar rashes.

For accurate diagnosis and treatment of Alzheimer's disease, precise quantification of amyloid beta (A) plaques is critical. Through the regulation of nitrogen atom positions and numbers, innovative, highly sensitive A tracers were created for this application. Different numbers and positions of nitrogen atoms were incorporated into a series of florbetapir (AV45) derivatives, which were then evaluated for in vitro affinity and in vivo biodistribution. Initial findings from the preliminary investigation demonstrated that [18F]BIBD-124 and [18F]BIBD-127 exhibited superior clearance rates and reduced in vivo defluorination compared to AV45 in ICR (Institute of Cancer Research) mice. Using autoradiography and molecular docking techniques, a similar binding site was observed for both [18F]BIBD-124/127 and [18F]AV45. The micro-positron emission tomography-computed tomography imaging further demonstrated that the ability of [18F]BIBD-124 to monitor A plaques resembled that of [18F]AV45. In addition, [18F]BIBD-124 exhibits superior imaging contrast compared to [18F]AV45. Mass spectrometric metabolic analysis found BIBD-124 to exhibit a lower level of demethylation than AV45, without subsequent acetylation, which could account for its reduced non-specific uptake and improved imaging contrast. Further analysis from Gauss confirmed that the introduction of N5 into the [18F]BIBD-124 structure was associated with a decrease in demethylation rates. Considering imaging contrast and in vivo defluorination factors, [18F]BIBD-124 holds significant promise as a radiotracer for A plaques, warranting further clinical investigation.

For several decades, the intricate mechanisms of cis-dihydroxylation of arenes and olefins, as catalyzed by Rieske dioxygenases and non-heme iron catalysts, and the characteristics of reactive intermediates involved, have been intensively investigated. This research reports the reactivity of a spectroscopically well-defined mononuclear non-heme iron(III)-peroxo complex toward olefins and naphthalene derivatives, ultimately yielding isolated and fully characterized iron(III) cycloadducts, both structurally and spectroscopically. Olefins and naphthalenes undergo reaction with the non-heme iron(III)-peroxo complex, a nucleophile, culminating in the formation of cis-diol products, as observed in kinetic and product analysis data. This study's findings reveal the initial example of a nonheme iron(III)-peroxo complex's ability to achieve cis-dihydroxylation of substrates, producing cis-diol products.

Using novel trajectory-based vowel space measures (hull area and density), this study examined whether these metrics' capacity to predict speech intelligibility in dysarthric speakers equaled that of conventional token-based vowel space area and corner dispersion. This investigation additionally probed if the correlation between acoustic vowel measurements and intelligibility scores varied based on the mode of intelligibility evaluation (orthographic transcriptions [OTs] or visual analog scale [VAS] ratings).
In a powerful and moving display of vocal dexterity, 40 speakers, all grappling with dysarthria due to diverse etiologies like Parkinson's disease, rendered the Grandfather Passage audibly.
In amyotrophic lateral sclerosis, commonly abbreviated as ALS, motor neurons undergo progressive degeneration.
The complex interplay of genetic predisposition and environmental factors contributes to the development of Huntington's disease.
Marked by cerebellar ataxia and the numerical designation ( = 10 ),.
This JSON schema stipulates a list of sentences as a return value. Using token- and trajectory-based methods, acoustic vowel measures were computed from the passage. Listeners without experience in discernment
A crowdsourced pool of 140 individuals was engaged to provide intelligibility ratings for both OTs and VAS. Hierarchical linear regression models were built to model the correlation between acoustic vowel measures and OTs and VAS intelligibility ratings.
Occupational therapists (OTs) found traditional VSA to be the sole decisive predictor of speech intelligibility.
A quarter of something, specifically 0.259, was the outcome. In relation to VAS,
Through careful calculation, a value of 0.236 was obtained. Perinatally HIV infected children Models, in their various forms, continue to be a remarkable advancement in technology. Plant stress biology The trajectory-derived measures, in contrast, exhibited no substantial predictive power regarding intelligibility. Furthermore, the OTs and VAS intelligibility assessments yielded comparable insights.
The findings posit that traditional token-based vowel measures better anticipate intelligibility compared to the trajectory-based measures. Importantly, the outcomes indicate that VAS procedures display comparability with OT methodologies when assessing speech intelligibility within research studies.
The study's findings reveal that traditional token-based vowel measurements are more effective at predicting intelligibility than trajectory-based ones. The study's results also show a similarity between VAS and OT approaches in evaluating speech comprehensibility for research.

Glaucoma surgeons are held in high regard by the general population. Shorter wait times and a younger age often contribute to higher ratings for the physicians providing care. Female glaucoma specialists are observed to be less prone to receiving top ratings.
Analyze the connection between glaucoma physician characteristics and better online reviews.
To ascertain data, the American Glaucoma Society (AGS) surveyed all its American members using Healthgrades, Vitals, and Yelp. Alizarin Carmine Detailed records were maintained for ratings, medical school ranking, region of practice, gender, age, and wait times.
A substantial 1106 (782%) of AGS members submitted at least one review across the three platforms. The mean score for glaucoma surgeons stands at 4160, demonstrating a standard deviation of 0898. The adjusted odds ratio for female physicians' online ratings was 0.536 (95% confidence interval: 0.354-0.808), suggesting a lower rating. A clear correlation emerged between reduced patient wait times and higher physician ratings. For wait times within the 15-30 minute range, the adjusted odds ratio was 2273 [95% CI 1430-3636], and for wait times under 15 minutes, the adjusted odds ratio was even higher at 3102 [95% CI 1888-5146]. Physicians of advanced years received lower appraisal scores, with an adjusted odds ratio of 0.384 (95% confidence interval: 0.255-0.572).
In the United States, online public ratings for glaucoma specialists appear to lean toward those of a younger age, male gender, and shorter waiting periods.
In the US, online public ratings for glaucoma specialists appear to be influenced by the specialist's age (younger), sex (male), and the time patients have to wait for appointments.

Analysis of historical cases of trabecular bypass microstent surgery and phacoemulsification demonstrated that the use of chronic antithrombotic therapy (ATT) was not associated with an elevated incidence of hemorrhagic complications. Female sex and the particular stent employed demonstrated an association with hyphema.
Reporting on the incidence of hemorrhagic events subsequent to trabecular bypass microstent implantation and phacoemulsification, either with or without ancillary trabeculectomy (ATT).
This retrospective case series, conducted between 2013 and 2019, evaluated glaucoma patients on long-term anti-tuberculosis therapy (ATT) who underwent both trabecular bypass microstent surgery (iStent, iStent inject, and Hydrus) and phacoemulsification, with a 3-month follow-up. The primary outcome was the rate of hemorrhagic complications experienced by patients within a three-month period following the surgical procedure. Inter-eye correlation was accommodated by the use of generalized estimating equations, followed by logistic regression to identify factors predicting hemorrhagic complications.
Of 333 patients (435 eyes), 161 patients (211 eyes) were treated with ATT and 172 patients (224 eyes) were not; both groups displayed similar age and baseline ocular health parameters. The sole hemorrhagic complication was hyphema, affecting 84 of the eyes (193%, 41 ATT, 43 non-ATT eyes; P = 100). In 988% of eyes, the condition started on postoperative day 1, and lasted one week in 738% of cases. No distinction was found between the ATT and non-ATT groups in this regard. Hydrus microstents were associated with a considerably greater incidence of hyphema (364%) than iStents (199%) and iStent injects (85%), showcasing a statistically significant difference (P = 0.0003). Multiple variables were considered in a model, and female sex was found to be a predictor for hyphema [hazard ratio (HR) = 2062; p-value = 0.0009]. On the other hand, iStent injection was found to have a protective effect against hyphema (HR = 0.379; p-value = 0.0033), whereas Hydrus showed no statistically significant association with hyphema (HR = 2.007; p-value = 0.0081).